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American Society of Microbiology ABMM Exam Syllabus Topics:

American Society of Microbiology ABMM Sample Questions:

1. A clinical microbiology laboratory is implementing a new laboratory information system (LIS). A critical step in the validation process is ensuring the accurate and reliable transfer of data, including patient demographics, test orders, and results. This aspect of validation primarily focuses on:

A) Clinical sensitivity and specificity.
B) Data integrity and interoperability.
C) Analytical sensitivity and specificity.
D) Workflow efficiency and user training.

2. A patient with AIDS develops a disseminated fungal infection. Blood cultures grow a yeast that produces pseudohyphae and terminal chlamydospores on cornmeal agar. The patient's CD4+ T-cell count is below 50 cells/µL. The MOST likely causative organism is:

A) Cryptococcus neoformans
B) Aspergillus fumigatus
C) Candida albicans
D) Pneumocystis jirovecii

3. Which pattern on a Kirby-Bauer disk diffusion plate, showing resistance of Staphylococcus aureus to erythromycin but susceptibility to clindamycin with a flattening of the clindamycin zone adjacent to the erythromycin disk (D-zone test positive), indicates inducible clindamycin resistance?

A) Indicates the strain possesses the msrA gene
B) Indicates the strain possesses an erm gene and should be reported as clindamycin resistant
C) Indicates the strain is tolerant to clindamycin
D) Indicates the strain should be reported as clindamycin susceptible

4. According to the current CDC-recommended laboratory algorithm for diagnosing HIV infection in adults and children aged >18 months, what is the recommended initial screening test?

A) HIV-1/HIV-2 antigen/antibody combination immunoassay
B) HIV-1 p24 antigen assay only
C) HIV RNA nucleic acid test (NAT)
D) HIV-1/HIV-2 antibody differentiation immunoassay

5. A patient with HIV infection and a CD4+ T-cell count below 100 cells/µL presents with headache, fever, and altered mental status. CSF analysis reveals elevated protein and low glucose. India ink stain is negative.
Cryptococcal antigen test of the CSF is positive. The MOST appropriate initial treatment is:

A) Caspofungin
B) Amphotericin B and flucytosine
C) Fluconazole
D) Voriconazole

Solutions: