USMLE USMLE Exam : United States Medical Licensing Examination

  • Exam Code: USMLE
  • Exam Name: United States Medical Licensing Examination
  • Updated: Jul 21, 2026
  • Q & A: 400 Questions and Answers

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USMLE Step 2 is open to all medical students and graduates who have successfully passed the USMLE Step 1. The Step 2 exam assesses the candidates' medical knowledge, skills, and understanding of clinical science essential for patient treatment and care, health promotion and disease prevention.

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USMLE United States Medical Licensing Examination

USMLE stands for United States Medical Licensing Examination. This is a series of medical exams coming in a few stages that all new doctors need to pass (starting from their time in med school) to be able to practice medicine.

Step 1 of the USMLE (United States Medical Licensing Examination) is the first part of the United States Medical Licensing Examination. It is open to medical school student and graduates to assess their ability to apply important concepts fundamental to the practice of medicine. While American medical students usually take USMLE Step 1 at the end of the second year of medical school, all graduates of foreign medical schools must take this exam is they intend to practice medicine in the United States.

Reference: http://www.usmle.org/step-1/#question-formats

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USMLE USMLE Exam Syllabus Topics:

SectionObjectives
Topic 1: Respiratory System- Pulmonary Medicine
  • 1. Lung Diseases
  • 2. Airway Disorders
Topic 2: Hematopoietic and Lymphoreticular Systems- Blood and Immune Disorders
  • 1. Leukemias and Lymphomas
  • 2. Anemias
  • 3. Coagulation Disorders
Topic 3: Cardiovascular System- Cardiac and Vascular Disorders
  • 1. Vascular Pathology
  • 2. Heart Disease
Topic 4: Renal and Urinary System- Kidney and Urinary Disorders
  • 1. Renal Physiology
  • 2. Renal Pathology
Topic 5: Endocrine System- Hormonal Regulation and Disease
  • 1. Pituitary Disorders
  • 2. Adrenal Disorders
  • 3. Thyroid Disorders
Topic 6: Central and Peripheral Nervous Systems- Neurologic Disorders
  • 1. Neuroanatomy
  • 2. Neurologic Diseases
  • 3. Neuropathology
Topic 7: Skin and Related Connective Tissue- Dermatologic Conditions
  • 1. Skin Neoplasms
  • 2. Inflammatory Skin Disorders
Topic 8: Reproductive System- Male and Female Reproductive Health
  • 1. Reproductive Disorders
  • 2. Reproductive Physiology
Topic 9: Multisystem Processes and Disorders- Systemic Conditions
  • 1. Neoplasia
  • 2. Nutrition
  • 3. Infectious Diseases
Topic 10: Musculoskeletal System- Bones, Joints, and Muscles
  • 1. Orthopedic Disorders
  • 2. Rheumatologic Diseases
Topic 11: General Principles- Foundational Medical Sciences
  • 1. Microbiology
  • 2. Physiology
  • 3. Genetics
  • 4. Pathology
  • 5. Pharmacology
  • 6. Behavioral Sciences
  • 7. Immunology
  • 8. Biochemistry
Topic 12: Human Development- Growth and Development
  • 1. Developmental Abnormalities
  • 2. Embryology
Topic 13: Gastrointestinal System- Digestive System Disorders
  • 1. Gastrointestinal Pathology
  • 2. Liver Disease

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